A thread lift and nasolabial fold filler can correct sagging and volume loss, but the crease that’s already set in, along with fine lines, may remain. Here’s why we pair them with skin boosters and radiofrequency treatments like Thermage, plus two real patient cases.

Hello from DAYONE Clinic. In our last post, we explained that nasolabial folds—the smile lines that run from the nose to the corners of the mouth—have two causes: sagging and volume loss. So if you lift with a thread lift and fill with nasolabial fold filler, is the problem completely solved? Today we’re looking at the next step.
Unfold a sheet of paper, and the crease remains
What happens when you fold a sheet of paper and then flatten it out? The paper lies flat again, but the fold line is still there. Nasolabial folds work the same way.
These lines form over many years of repeated sagging and volume loss. So even after a thread lift pulls the tissue up and filler restores lost volume, the crease that’s already formed may not disappear completely. Fine lines tend to stay, too. That’s where adding certain treatments can take your results further.

Treating fine lines and firmness
Think of ironing a shirt. Running a dry iron over it does smooth things out to a degree. But the small wrinkles won’t come out unless you spritz on some water. Skin boosters and radiofrequency treatments play the role of that water.

Skin boosters (Rejuran, Re2O, and others)—These deliver ingredients such as hyaluronic acid, PDRN, and collagen directly into the skin. By replenishing hydration and nutrients, they help soften fine lines and improve elasticity.
Radiofrequency treatments like Thermage—These use radiofrequency energy to stimulate collagen production and restore the skin’s own firmness. They target fine lines while also smoothing skin texture.
When these two are combined with a thread lift and nasolabial fold filler, the improvement can go beyond the smile lines themselves to the overall contours and texture of the skin.
Real patient cases
One patient, a woman in her late 50s, had a combination of sagging and volume loss. We lifted the upper area with a thread lift, placed a small amount of filler in the hollows, used Ultherapy so we didn’t have to rely as heavily on volume, and finished with a skin booster to address fine lines. Her smile lines faded overall, and her facial contours and skin texture improved as well.

Another patient came in concerned about both nasolabial folds and marionette lines. We started with a thread lift and filler as the foundation and added a skin booster. Her smile lines softened, her overall firmness held up, and her fine lines improved.
The bottom line
In short:
Sagging—lift with a thread lift
Volume loss—fill with nasolabial fold filler
Lingering fine lines and laxity—finish with skin boosters and radiofrequency treatments like Thermage
When all three work together, you can get the most satisfying results. If you have any questions, feel free to reach out anytime.
This post is based on an interview from DAYONE Clinic’s YouTube channel, Face Design Lab.
This article is general information about the treatment and does not replace an individual diagnosis or treatment plan. Results and their duration vary from person to person.
Wondering what would suit you?
Whether a treatment suits you, and how to plan it, is best decided with a doctor.